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Lead optimization and efficacy evaluation of quinazoline-based BET family inhibitors for potential treatment of cancer and inflammatory diseases.
Yang, Shyh-Ming; Yoshioka, Makoto; Strovel, Jeffrey W; Urban, Daniel J; Hu, Xin; Hall, Matthew D; Jadhav, Ajit; Maloney, David J.
Afiliação
  • Yang SM; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States. Electronic address: yangs9@mail.nih.gov.
  • Yoshioka M; ConverGene LLC., 3093 Beverly Lane, Unit C, Cambridge, MD 21613, United States.
  • Strovel JW; ConverGene LLC., 3093 Beverly Lane, Unit C, Cambridge, MD 21613, United States.
  • Urban DJ; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Hu X; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Jadhav A; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Maloney DJ; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States. Electronic address: dave@NexusDA.com.
Bioorg Med Chem Lett ; 29(10): 1220-1226, 2019 05 15.
Article em En | MEDLINE | ID: mdl-30905542
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Fatores de Transcrição / Proteínas de Ciclo Celular / Anti-Inflamatórios / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Fatores de Transcrição / Proteínas de Ciclo Celular / Anti-Inflamatórios / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article