KLF9 suppresses gastric cancer cell invasion and metastasis through transcriptional inhibition of MMP28.

Li, Yang; Sun, Qiang; Jiang, Mingchun; Li, Shuang; Zhang, Jiayu; Xu, Zhangqi; Guo, Dongyang; Gu, Tianning; Wang, Boya; Xiao, Lei; Zhou, Tianhua; Zhuo, Wei

Li, Yang; Sun, Qiang; Jiang, Mingchun; Li, Shuang; Zhang, Jiayu; Xu, Zhangqi; Guo, Dongyang; Gu, Tianning; Wang, Boya; Xiao, Lei; Zhou, Tianhua; Zhuo, Wei.

Afiliação

Li Y; College of Animal Science, Zhejiang University, Hangzhou, China.
Sun Q; Department of Cell Biology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jiang M; Department of Cell Biology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Li S; Department of Cell Biology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhang J; Department of Cell Biology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xu Z; Department of Cell Biology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Guo D; Department of Cell Biology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Gu T; Department of Cell Biology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wang B; Department of Cell Biology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiao L; Department of Pharmacy, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhou T; College of Animal Science, Zhejiang University, Hangzhou, China.
Zhuo W; Department of Cell Biology and Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

FASEB J ; 33(7): 7915-7928, 2019 07.

Article em En | MEDLINE | ID: mdl-30913394

Assuntos

Regulação Neoplásica da Expressão Gênica/genética; Fatores de Transcrição Kruppel-Like/fisiologia; Metaloproteinases da Matriz Secretadas/genética; Invasividade Neoplásica/genética; Metástase Neoplásica/genética; Proteínas de Neoplasias/fisiologia; Neoplasias Gástricas/patologia; Transcrição Gênica/genética; Animais; Linhagem Celular Tumoral; Técnicas de Silenciamento de Genes; Xenoenxertos; Humanos; Fatores de Transcrição Kruppel-Like/deficiência; Fatores de Transcrição Kruppel-Like/genética; Neoplasias Pulmonares/prevenção & controle; Neoplasias Pulmonares/secundário; Metaloproteinases da Matriz Secretadas/biossíntese; Camundongos; Camundongos SCID; Proteínas de Neoplasias/biossíntese; Proteínas de Neoplasias/genética; Transplante de Neoplasias; Proteínas Recombinantes/metabolismo; Organismos Livres de Patógenos Específicos; Neoplasias Gástricas/genética; Transfecção

Palavras-chave

GSEA; MTT assay; pulmonary metastasis; stomach; transwell assay

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Transcrição Gênica / Regulação Neoplásica da Expressão Gênica / Fatores de Transcrição Kruppel-Like / Metaloproteinases da Matriz Secretadas / Invasividade Neoplásica / Metástase Neoplásica / Proteínas de Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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