Energy expenditure in chronic alcoholics with and without liver disease.
Am J Clin Nutr
; 44(3): 323-9, 1986 Sep.
Article
em En
| MEDLINE
| ID: mdl-3092630
ABSTRACT
Chronic alcoholism activates metabolic pathways, resulting in wasteful expenditure of energy (Pirola and Lieber, J Nutr 1975;1051544-8). To study this hypothesis, we measured oxygen consumption (VO2), carbon dioxide production (VCO2), and resting energy expenditure (MREE) utilizing indirect calorimetry in 8 chronic alcoholics with (group I) and 11 chronic alcoholics without (group II) clinical or biochemical evidence of alcoholic liver disease. Seven healthy volunteers served as controls. A statistically increased MREE was observed in group II subjects (p less than 0.05, MREE 999.7 +/- 111.4 kcal X day X m2) as compared to normals (MREE 842.3 +/- 42.1 kcal X day X m2) and group I subjects (MREE 813.4 +/- 101.4 kcal X day X m2). VO2 and VCO2 were also significantly higher (p less than 0.05) in group II than in group I and normals. The predicted resting energy expenditure as calculated by the Harris-Benedict equation was similar in both groups and normals. Theories to explain the increased MREE in group II subjects are presented.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Alcoolismo
/
Metabolismo Energético
/
Hepatopatias Alcoólicas
Tipo de estudo:
Health_economic_evaluation
Limite:
Adult
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
1986
Tipo de documento:
Article