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Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position.
Gálvez, José A; Clavería-Gimeno, Rafael; Galano-Frutos, Juan J; Sancho, Javier; Velázquez-Campoy, Adrian; Abian, Olga; Díaz-de-Villegas, María D.
Afiliação
  • Gálvez JA; Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC - Universidad de Zaragoza, Departamento de Química Orgánica, Pedro Cerbuna 12, 50009 Zaragoza, Spain. Electronic address: jagl@unizar.es.
  • Clavería-Gimeno R; Instituto Aragonés de Ciencias de la Salud (IACS), 50009 Zaragoza, Spain; Biocomputation and Complex Systems Physics Institute (BIFI)-Joint Units: BIFI-IQFR (CSIC) and GBsC-CSIC, University of Zaragoza, Zaragoza 50018, Spain.
  • Galano-Frutos JJ; Biocomputation and Complex Systems Physics Institute (BIFI)-Joint Units: BIFI-IQFR (CSIC) and GBsC-CSIC, University of Zaragoza, Zaragoza 50018, Spain; Aragon Institute for Health Research (IIS Aragon), 50009 Zaragoza, Spain; Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Cie
  • Sancho J; Biocomputation and Complex Systems Physics Institute (BIFI)-Joint Units: BIFI-IQFR (CSIC) and GBsC-CSIC, University of Zaragoza, Zaragoza 50018, Spain; Aragon Institute for Health Research (IIS Aragon), 50009 Zaragoza, Spain; Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Cie
  • Velázquez-Campoy A; Biocomputation and Complex Systems Physics Institute (BIFI)-Joint Units: BIFI-IQFR (CSIC) and GBsC-CSIC, University of Zaragoza, Zaragoza 50018, Spain; Fundación ARAID, Government of Aragon, Zaragoza, Spain; Centro de Investigación Biomédica en Red en el Área Temática de Enfermedades Hepáticas y Dig
  • Abian O; Instituto Aragonés de Ciencias de la Salud (IACS), 50009 Zaragoza, Spain; Biocomputation and Complex Systems Physics Institute (BIFI)-Joint Units: BIFI-IQFR (CSIC) and GBsC-CSIC, University of Zaragoza, Zaragoza 50018, Spain; Aragon Institute for Health Research (IIS Aragon), 50009 Zaragoza, Spain;
  • Díaz-de-Villegas MD; Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC - Universidad de Zaragoza, Departamento de Química Orgánica, Pedro Cerbuna 12, 50009 Zaragoza, Spain. Electronic address: loladiaz@unizar.es.
Eur J Med Chem ; 171: 401-419, 2019 Jun 01.
Article em En | MEDLINE | ID: mdl-30928711
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / RNA Polimerases Dirigidas por DNA / Hepacivirus Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / RNA Polimerases Dirigidas por DNA / Hepacivirus Idioma: En Ano de publicação: 2019 Tipo de documento: Article