A unified (but in fact not fully testable) model of preeclampsia triggering.
J Reprod Immunol
; 132: 49-53, 2019 04.
Article
em En
| MEDLINE
| ID: mdl-30947086
ABSTRACT
In this summary of my presentation in the last Reunion workshop I discuss a few assertions on preeclampsia, then turn on a (not fully testable) model where an embryonic defect in expression of embryo/ placental regulatory proteins results in complement activation, itself responsible for a down regulation of the T regs activity, resulting in a very early lack of complete down regulation of the preimplantation decidual inflammation, causing in the post implantation stage a low grade but chronic inflammatory state.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pré-Eclâmpsia
/
Linfócitos T Reguladores
/
Ativação do Complemento
/
Decídua
/
Modelos Biológicos
Limite:
Animals
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article