Hyperuricemia and Cardiovascular Disease.
Curr Pharm Des
; 25(6): 700-709, 2019.
Article
em En
| MEDLINE
| ID: mdl-30961478
ABSTRACT
Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely correlated with cardiovascular disease, metabolic syndrome, and chronic kidney disease, as attested by the epidemiological and empirical research. In this review, we summarize the recent knowledge about hyperuricemia, with a special focus on its physiology, epidemiology, and correlation with cardiovascular disease. This review also discusses the possible positive effects of treatment to reduce urate levels in patients with cardiovascular disease and hyperuricemia, which may lead to an improved clinical treatment plan.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Úrico
/
Doenças Cardiovasculares
/
Hiperuricemia
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article