The structure of Trametes versicolor glutathione transferase Omega 3S bound to its conjugation product glutathionyl-phenethylthiocarbamate reveals plasticity of its active site.

Schwartz, Mathieu; Perrot, Thomas; Morel-Rouhier, Mélanie; Mulliert, Guillermo; Gelhaye, Eric; Didierjean, Claude; Favier, Frédérique

Schwartz, Mathieu; Perrot, Thomas; Morel-Rouhier, Mélanie; Mulliert, Guillermo; Gelhaye, Eric; Didierjean, Claude; Favier, Frédérique.

Afiliação

Schwartz M; Université de Lorraine, CNRS, CRM2, Nancy, France.
Perrot T; Université de Lorraine, INRA, IAM, Nancy, France.
Morel-Rouhier M; Université de Lorraine, INRA, IAM, Nancy, France.
Mulliert G; Université de Lorraine, CNRS, CRM2, Nancy, France.
Gelhaye E; Université de Lorraine, INRA, IAM, Nancy, France.
Didierjean C; Université de Lorraine, CNRS, CRM2, Nancy, France.
Favier F; Université de Lorraine, CNRS, CRM2, Nancy, France.

Protein Sci ; 28(6): 1143-1150, 2019 06.

Article em En | MEDLINE | ID: mdl-30972861

Assuntos

Glutationa Transferase/química; Glutationa/biossíntese; Isotiocianatos/metabolismo; Trametes/enzimologia; Sítios de Ligação; Biocatálise; Glutationa/química; Glutationa Transferase/metabolismo; Isotiocianatos/química; Modelos Moleculares; Estrutura Molecular

Palavras-chave

Trametes versicolor; X-ray crystallography; glutathione transferase; isothiocyanate; polyphenols

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Isotiocianatos / Trametes / Glutationa / Glutationa Transferase Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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