Successful treatment of spindle cell hemangiomas in a patient with Maffucci syndrome and review of literatures.

Lekwuttikarn, Ramrada; Chang, James; Teng, Joyce M C

Lekwuttikarn, Ramrada; Chang, James; Teng, Joyce M C.

Afiliação

Lekwuttikarn R; Department of Dermatology, Division of Pediatric Dermatology, Stanford University School of Medicine, Stanford, California.
Chang J; Department of Pediatrics, Division of Ambulatory and Adolescent Medicine, Section of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Teng JMC; Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Stanford, California.

Dermatol Ther ; 32(3): e12919, 2019 05.

Article em En | MEDLINE | ID: mdl-30977938

RESUMO

Maffucci syndrome is a rare genetic disease due to somatic mutation of IDH1 gene. Currently there is no medical treatment available for spindle cell hemangioma associated with this disorder. Here we report successful management of these hemangiomas using sirolimus in combination with surgery.

Assuntos

Encondromatose/complicações; Hemangioma/terapia; Adulto; Feminino; Humanos; Sirolimo/uso terapêutico

Palavras-chave

IDH 1 mutation; Maffucci syndrome; sirolimus; spindle cell hemangioma

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encondromatose / Hemangioma Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google