Development of a Synthetic 3-ketosteroid &#916;<sup>1</sup>-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells.

D'Arcy, Brandon M; Swingle, Mark R; Schambeau, Lindsay; Pannell, Lewis; Prakash, Aishwarya; Honkanen, Richard E

Development of a Synthetic 3-ketosteroid Δ¹-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells.

D'Arcy, Brandon M; Swingle, Mark R; Schambeau, Lindsay; Pannell, Lewis; Prakash, Aishwarya; Honkanen, Richard E.

Afiliação

D'Arcy BM; Department of Biochemistry & Molecular Biology, University of South Alabama, Mobile, AL, 36688, USA.
Swingle MR; Mitchell Cancer Institute, 1660 Springhill Ave, Mobile, AL, 36604, USA.
Schambeau L; Department of Biochemistry & Molecular Biology, University of South Alabama, Mobile, AL, 36688, USA.
Pannell L; Mitchell Cancer Institute, 1660 Springhill Ave, Mobile, AL, 36604, USA.
Prakash A; Mitchell Cancer Institute, 1660 Springhill Ave, Mobile, AL, 36604, USA.
Honkanen RE; Mitchell Cancer Institute, 1660 Springhill Ave, Mobile, AL, 36604, USA.

Sci Rep ; 9(1): 5969, 2019 04 12.

Article em En | MEDLINE | ID: mdl-30979909

Assuntos

Colesterol/metabolismo; Oxirredutases/química; Oxirredutases/metabolismo; Linhagem Celular; Escherichia coli; Engenharia Genética; Humanos; Oxirredutases/genética; Estudo de Prova de Conceito

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxirredutases / Colesterol Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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