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CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML.
Vinyard, Michael E; Su, Cindy; Siegenfeld, Allison P; Waterbury, Amanda L; Freedy, Allyson M; Gosavi, Pallavi M; Park, Yongho; Kwan, Eugene E; Senzer, Benjamin D; Doench, John G; Bauer, Daniel E; Pinello, Luca; Liau, Brian B.
Afiliação
  • Vinyard ME; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Su C; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Siegenfeld AP; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Waterbury AL; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Freedy AM; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Gosavi PM; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Park Y; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Kwan EE; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Senzer BD; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Doench JG; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Bauer DE; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.
  • Pinello L; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Liau BB; Department of Pediatrics, Harvard Medical School and Harvard Stem Cell Institute, Harvard University, Boston, MA, USA.
Nat Chem Biol ; 15(5): 529-539, 2019 05.
Article em En | MEDLINE | ID: mdl-30992567
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Histona Desmetilases / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Histona Desmetilases / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article