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Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.
Crespo, Roberto A; Dang, Qun; Zhou, Nian E; Guthrie, Liam M; Snavely, Thomas C; Dong, Wen; Loesch, Kimberly A; Suzuki, Takao; You, Lanying; Wang, Wei; O'Malley, Theresa; Parish, Tanya; Olsen, David B; Sacchettini, James C.
Afiliação
  • Crespo RA; Department of Biochemistry and Biophysics , Texas A&M University , College Station , Texas 77843 , United States.
  • Dang Q; Merck Sharp Dohme Corporation , West Point Pennsylvania 19486 , United States.
  • Zhou NE; Department of Biochemistry and Biophysics , Texas A&M University , College Station , Texas 77843 , United States.
  • Guthrie LM; College of Medicine , Texas A&M University Health Science Center , Bryan , Texas 77807 , United States.
  • Snavely TC; Department of Biochemistry and Biophysics , Texas A&M University , College Station , Texas 77843 , United States.
  • Dong W; Department of Biochemistry and Biophysics , Texas A&M University , College Station , Texas 77843 , United States.
  • Loesch KA; Department of Biochemistry and Biophysics , Texas A&M University , College Station , Texas 77843 , United States.
  • Suzuki T; WuXi AppTec , 288 Fute Zhong Road , Shanghai 200131 , China.
  • You L; WuXi AppTec , 288 Fute Zhong Road , Shanghai 200131 , China.
  • Wang W; WuXi AppTec , 288 Fute Zhong Road , Shanghai 200131 , China.
  • O'Malley T; TB Discovery Research , Infectious Disease Research Institute , 1616 Eastlake Avenue E , Seattle , Washington 98102 , United States.
  • Parish T; TB Discovery Research , Infectious Disease Research Institute , 1616 Eastlake Avenue E , Seattle , Washington 98102 , United States.
  • Olsen DB; Merck Sharp Dohme Corporation , West Point Pennsylvania 19486 , United States.
  • Sacchettini JC; Department of Biochemistry and Biophysics , Texas A&M University , College Station , Texas 77843 , United States.
J Med Chem ; 62(9): 4483-4499, 2019 05 09.
Article em En | MEDLINE | ID: mdl-31002508
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Adenosina / Adenosina Quinase / Inibidores de Proteínas Quinases / Mycobacterium tuberculosis Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Adenosina / Adenosina Quinase / Inibidores de Proteínas Quinases / Mycobacterium tuberculosis Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article