Small Molecules with Big Promises for Curing Demyelinating Diseases.

Han, Fangbin; Zhou, Ming-Ming

Han, Fangbin; Zhou, Ming-Ming.

Afiliação

Han F; Bethune Institute of Epigenetic Medicine, The First Hospital, Jilin University, Changchun 130021, China.
Zhou MM; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: ming-ming.zhou@mssm.edu.

Cell Chem Biol ; 26(4): 468-470, 2019 04 18.

Article em En | MEDLINE | ID: mdl-31002801

ABSTRACT

ABSTRACT

Myelin regeneration by myelinating oligodendrocytes is key to neuronal damage repair for treatment of neurological disorders such as multiple sclerosis. In this issue of Cell Chemical Biology, Allimuthu et al. (2019) report new small molecule inhibitors of cholesterol biosynthesis enzymes that enhance oligodendrocyte formation and subsequent remyelination.

Assuntos

Esclerose Múltipla; Oligodendroglia; Humanos; Bainha de Mielina

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligodendroglia / Esclerose Múltipla Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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