Acute fructose intake suppresses fasting-induced hepatic gluconeogenesis through the AKT-FoxO1 pathway.

Sato, Tomoki; Watanabe, Yui; Nishimura, Yuri; Inoue, Mizuki; Morita, Akihito; Miura, Shinji

Sato, Tomoki; Watanabe, Yui; Nishimura, Yuri; Inoue, Mizuki; Morita, Akihito; Miura, Shinji.

Afiliação

Sato T; Laboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Watanabe Y; Research Fellow of Japan Society for the Promotion of Science, 5-3-1 Kojimachi, Chiyoda-ku, Tokyo, 102-0083, Japan.
Nishimura Y; Laboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Inoue M; Laboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Morita A; Laboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Miura S; Laboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

Biochem Biophys Rep ; 18: 100638, 2019 Jul.

Article em En | MEDLINE | ID: mdl-31032430

Palavras-chave

AKT; CREB, cAMP response element binding protein; ChREBP, carbohydrate response element binding protein; EDTA, ethylenediaminetetraacetic acid; FFA, free fatty acid; FoxO, forkhead box O; FoxO1; Fructose; G6Pase; G6Pase, glucose-6-phosphatase; Gluconeogenesis; Insulin; PEPCK, phosphoenolpyruvate carboxykinase; PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1 alpha; PI3K, phosphoinositide-3-kinase; PIP 3, phosphatidylinositol-(3,4,5)-trisphosphate; SREBP, sterol-regulatory element binding protein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article