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Increasing Diagnostic Uncertainties in Children With In Utero HIV Infection.
Millar, Jane R; Mvo, Zodumo; Bengu, Nomonde; Fillis, Rowena; Sprenger, Ken; Matthews, Philippa C; Archary, Moherndran; Ndung'u, Thumbi; Adland, Emily; Puertas, Maria C; Martinez-Picado, Javier; Goulder, Philip.
Afiliação
  • Millar JR; Umkhuseli Innovation and Research Management, Pietermaritzburg, South Africa.
  • Mvo Z; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
  • Bengu N; Umkhuseli Innovation and Research Management, Pietermaritzburg, South Africa.
  • Fillis R; Umkhuseli Innovation and Research Management, Pietermaritzburg, South Africa.
  • Sprenger K; Umkhuseli Innovation and Research Management, Pietermaritzburg, South Africa.
  • Matthews PC; Umkhuseli Innovation and Research Management, Pietermaritzburg, South Africa.
  • Archary M; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
  • Ndung'u T; Department of Paediatrics, University of KwaZulu-Natal, Durban, South Africa.
  • Adland E; Ragon Institute of MGH, MIT and Havard, Cambridge, MA, USA.
  • Puertas MC; Africa Health Research Institute, Durban, South Africa.
  • Martinez-Picado J; Max Planck Institute for Infection Biology, Berlin, Germany.
  • Goulder P; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Pediatr Infect Dis J ; 38(8): e166-e168, 2019 08.
Article em En | MEDLINE | ID: mdl-31033913
ABSTRACT
We present a case of an in utero HIV-infected child, who on day 1 of life had a positive whole blood total nucleic acid test but viral load <20 RNA copies/mL. Dried blood spot total nucleic acid testing was negative on day 1, 10 and at 3 months, while on ART prophylaxis then positive at 5 months after prophylaxis ended. Retrospective peripheral blood mononuclear cells HIV DNA testing from day 1 of life was positive, confirming in utero infection.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Transmissão Vertical de Doenças Infecciosas Tipo de estudo: Diagnostic_studies Limite: Child / Female / Humans / Newborn Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Transmissão Vertical de Doenças Infecciosas Tipo de estudo: Diagnostic_studies Limite: Child / Female / Humans / Newborn Idioma: En Ano de publicação: 2019 Tipo de documento: Article