Omega-3 fatty acids are protective in hepatic ischemia reperfusion injury in the absence of GPR120 signaling.

Baker, Meredith A; Nandivada, Prathima; Mitchell, Paul D; Fell, Gillian L; Pan, Amy; Cho, Bennet S; De La Flor, Denis J; Anez-Bustillos, Lorenzo; Dao, Duy T; Nosé, Vania; Puder, Mark

Baker, Meredith A; Nandivada, Prathima; Mitchell, Paul D; Fell, Gillian L; Pan, Amy; Cho, Bennet S; De La Flor, Denis J; Anez-Bustillos, Lorenzo; Dao, Duy T; Nosé, Vania; Puder, Mark.

Afiliação

Baker MA; Vascular Biology Program and Department of Surgery, Boston Children's Hospital.
Nandivada P; Vascular Biology Program and Department of Surgery, Boston Children's Hospital.
Mitchell PD; Institutional Centers for Clinical and Translational Research, Boston Children's Hospital.
Fell GL; Vascular Biology Program and Department of Surgery, Boston Children's Hospital.
Pan A; Vascular Biology Program and Department of Surgery, Boston Children's Hospital.
Cho BS; Vascular Biology Program and Department of Surgery, Boston Children's Hospital.
De La Flor DJ; Vascular Biology Program and Department of Surgery, Boston Children's Hospital.
Anez-Bustillos L; Vascular Biology Program and Department of Surgery, Boston Children's Hospital.
Dao DT; Vascular Biology Program and Department of Surgery, Boston Children's Hospital.
Nosé V; Department of Pathology, Massachusetts General Hospital.
Puder M; Vascular Biology Program and Department of Surgery, Boston Children's Hospital. Electronic address: mark.puder@childrens.harvard.edu.

J Pediatr Surg ; 54(11): 2392-2397, 2019 Nov.

Article em En | MEDLINE | ID: mdl-31036368

Assuntos

Ácidos Graxos Ômega-3/farmacologia; Receptores Acoplados a Proteínas G/efeitos dos fármacos; Traumatismo por Reperfusão/prevenção & controle; Alanina Transaminase/sangue; Animais; Proliferação de Células; Hepatócitos/citologia; Fígado/metabolismo; Fígado/patologia; Masculino; Camundongos Endogâmicos C57BL; Camundongos Knockout; Subunidade p50 de NF-kappa B/metabolismo; Necrose/patologia; Traumatismo por Reperfusão/patologia; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Fish oil; Free fatty acid receptor 4; GPR120; Ischemia; Liver; Reperfusion

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Ácidos Graxos Ômega-3 / Receptores Acoplados a Proteínas G Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google