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EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy.
Puppe, Julian; Opdam, Mark; Schouten, Philip C; Józwiak, Katarzyna; Lips, Esther; Severson, Tesa; van de Ven, Marieke; Brambillasca, Chiara; Bouwman, Peter; van Tellingen, Olaf; Bernards, René; Wesseling, Jelle; Eichler, Christian; Thangarajah, Fabinshy; Malter, Wolfram; Pandey, Gaurav Kumar; Ozretic, Luka; Caldas, Carlos; van Lohuizen, Maarten; Hauptmann, Michael; Rhiem, Kerstin; Hahnen, Eric; Reinhardt, H Christian; Büttner, Reinhard; Mallmann, Peter; Schömig-Markiefka, Birgid; Schmutzler, Rita; Linn, Sabine; Jonkers, Jos.
Afiliação
  • Puppe J; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. julian.puppe@uk-koeln.de.
  • Opdam M; Department of Obstetrics and Gynecology, Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • Schouten PC; Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.
  • Józwiak K; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Lips E; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Severson T; Department of Epidemiology and Biostatistics, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • van de Ven M; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Brambillasca C; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Bouwman P; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • van Tellingen O; Oncode Institute, Utrecht, the Netherlands.
  • Bernards R; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Wesseling J; Oncode Institute, Utrecht, the Netherlands.
  • Eichler C; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Thangarajah F; Oncode Institute, Utrecht, the Netherlands.
  • Malter W; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Pandey GK; Oncode Institute, Utrecht, the Netherlands.
  • Ozretic L; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Caldas C; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • van Lohuizen M; Department of Obstetrics and Gynecology, Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • Hauptmann M; Department of Obstetrics and Gynecology, Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • Rhiem K; Department of Obstetrics and Gynecology, Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • Hahnen E; Oncode Institute, Utrecht, the Netherlands.
  • Reinhardt HC; Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Büttner R; Department of Pathology, University Hospital of Cologne, Cologne, Germany.
  • Mallmann P; CRUK Cambridge Institute, Cambridge, UK.
  • Schömig-Markiefka B; Oncode Institute, Utrecht, the Netherlands.
  • Schmutzler R; Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Linn S; Department of Epidemiology and Biostatistics, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Jonkers J; Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.
Clin Cancer Res ; 25(14): 4351-4362, 2019 07 15.
Article em En | MEDLINE | ID: mdl-31036541
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Platina / Neoplasias da Mama / Biomarcadores Tumorais / Neoplasias Mamárias Animais / Proteína BRCA1 / Proteína Potenciadora do Homólogo 2 de Zeste Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Platina / Neoplasias da Mama / Biomarcadores Tumorais / Neoplasias Mamárias Animais / Proteína BRCA1 / Proteína Potenciadora do Homólogo 2 de Zeste Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article