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Fungus Among Us: The Frenemies Within.
Aggor, Felix E Y; Way, Sing Sing; Gaffen, Sarah L.
Afiliação
  • Aggor FEY; University of Pittsburgh, Department of Medicine, Division of Rheumatology and Clinical Immunology, Pittsburgh, PA 15261, USA.
  • Way SS; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.
  • Gaffen SL; University of Pittsburgh, Department of Medicine, Division of Rheumatology and Clinical Immunology, Pittsburgh, PA 15261, USA. Electronic address: Sarah.gaffen@pitt.edu.
Trends Immunol ; 40(6): 469-471, 2019 06.
Article em En | MEDLINE | ID: mdl-31053496
ABSTRACT
A recent study shows that the commensal fungus Candida albicans is an inducer of differentiation of human CD4+ Th17 cells that harbor heterologous specificity for other fungi, which may explain evolutionary benefits of C. albicans as a commensal microbe (Bacher et al. Cell 2019;176;1340-1355). However, Th17 cells that are crossreactive to Aspergillus fumigatus antigens can also drive exaggerated airway inflammation in humans.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Candida albicans / Células Th17 Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Candida albicans / Células Th17 Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article