Bridging the gap: Mechanisms of plasticity and repair after pediatric TBI.
Exp Neurol
; 318: 78-91, 2019 08.
Article
em En
| MEDLINE
| ID: mdl-31055004
ABSTRACT
Traumatic brain injury is the leading cause of death and disability in the United States, and may be associated with long lasting impairments into adulthood. The multitude of ongoing neurobiological processes that occur during brain maturation confer both considerable vulnerability to TBI but may also provide adaptability and potential for recovery. This review will examine and synthesize our current understanding of developmental neurobiology in the context of pediatric TBI. Delineating this biology will facilitate more targeted initial care, mechanism-based therapeutic interventions and better long-term prognostication and follow-up.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Recuperação de Função Fisiológica
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Lesões Encefálicas Traumáticas
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Regeneração Nervosa
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Plasticidade Neuronal
Limite:
Child
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Child, preschool
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Humans
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Infant
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Newborn
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article