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Safety of intradiscal delivery of triamcinolone acetonide by a poly(esteramide) microsphere platform in a large animal model of intervertebral disc degeneration.
Rudnik-Jansen, Imke; Tellegen, Anna; Beukers, Martijn; Öner, Fetullah; Woike, Nina; Mihov, George; Thies, Jens; Meij, Björn; Tryfonidou, Marianna; Creemers, Laura.
Afiliação
  • Rudnik-Jansen I; Department of Orthopaedics, University Medical Center Utrecht, HP G05.228, Postbus 85500, Heidelberglaan 100, 3508GA Utrecht, The Netherlands.
  • Tellegen A; Department of Clinical Sciences of Companion Animals, Yalelaan 108, 3584 CM Utrecht, The Netherlands.
  • Beukers M; Department of Clinical Sciences of Companion Animals, Yalelaan 108, 3584 CM Utrecht, The Netherlands.
  • Öner F; Department of Orthopaedics, University Medical Center Utrecht, HP G05.228, Postbus 85500, Heidelberglaan 100, 3508GA Utrecht, The Netherlands.
  • Woike N; DSM Biomedical B.V., Koestraat 1, 6167 RA Geleen, The Netherlands.
  • Mihov G; DSM Biomedical B.V., Koestraat 1, 6167 RA Geleen, The Netherlands.
  • Thies J; DSM Biomedical B.V., Koestraat 1, 6167 RA Geleen, The Netherlands.
  • Meij B; Department of Clinical Sciences of Companion Animals, Yalelaan 108, 3584 CM Utrecht, The Netherlands.
  • Tryfonidou M; Department of Clinical Sciences of Companion Animals, Yalelaan 108, 3584 CM Utrecht, The Netherlands.
  • Creemers L; Department of Orthopaedics, University Medical Center Utrecht, HP G05.228, Postbus 85500, Heidelberglaan 100, 3508GA Utrecht, The Netherlands. Electronic address: l.b.creemers@umcutrecht.nl.
Spine J ; 19(5): 905-919, 2019 05.
Article em En | MEDLINE | ID: mdl-31056104

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triancinolona Acetonida / Portadores de Fármacos / Degeneração do Disco Intervertebral / Microesferas / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triancinolona Acetonida / Portadores de Fármacos / Degeneração do Disco Intervertebral / Microesferas / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article