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Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models.
Karol, Seth E; Janke, Laura J; Panetta, John C; Ramsey, Laura B; Cai, Xiangjun; Payton, Monique A; Jenkins, David A; Evans, William E; Relling, Mary V.
Afiliação
  • Karol SE; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
  • Janke LJ; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
  • Panetta JC; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
  • Ramsey LB; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
  • Cai X; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
  • Payton MA; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
  • Jenkins DA; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
  • Evans WE; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
  • Relling MV; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
PLoS One ; 14(5): e0216328, 2019.
Article em En | MEDLINE | ID: mdl-31059548
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteonecrose / Asparaginase / Dexametasona / Protocolos de Quimioterapia Combinada Antineoplásica / Leucemia-Linfoma Linfoblástico de Células Precursoras Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteonecrose / Asparaginase / Dexametasona / Protocolos de Quimioterapia Combinada Antineoplásica / Leucemia-Linfoma Linfoblástico de Células Precursoras Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article