Involvement of C/EBPß-related signaling pathway in methamphetamine-induced neuronal autophagy and apoptosis.

Huang, Enping; Huang, Hongyan; Guan, Tianshan; Liu, Chao; Qu, Dong; Xu, Yue; Yang, Jiao; Yan, Lei; Xiong, Yahui; Liang, Ting; Wang, Qi; Chen, Ling

Huang, Enping; Huang, Hongyan; Guan, Tianshan; Liu, Chao; Qu, Dong; Xu, Yue; Yang, Jiao; Yan, Lei; Xiong, Yahui; Liang, Ting; Wang, Qi; Chen, Ling.

Afiliação

Huang E; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, People's Republic of China.
Huang H; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, People's Republic of China.
Guan T; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, People's Republic of China.
Liu C; Guangzhou Forensic Science Institute, Guangzhou 510030, People's Republic of China.
Qu D; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, People's Republic of China.
Xu Y; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, People's Republic of China.
Yang J; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, People's Republic of China.
Yan L; School of Basic Medicine Science, Southern Medical University, Guangzhou 510515, People's Republic of China.
Xiong Y; Nanfang Hospital, Southern Medical University, The First Clinical Medicine School, Southern Medical University, Guangzhou 510515, People's Republic of China.
Liang T; Nanfang Hospital, Southern Medical University, The First Clinical Medicine School, Southern Medical University, Guangzhou 510515, People's Republic of China.
Wang Q; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, People's Republic of China. Electronic address: wangqi_legmed@126.com.
Chen L; School of Forensic Medicine, Southern Medical University, Guangzhou 510515, People's Republic of China. Electronic address: lingpzy@163.com.

Toxicol Lett ; 312: 11-21, 2019 Sep 15.

Article em En | MEDLINE | ID: mdl-31059759

Assuntos

Apoptose/efeitos dos fármacos; Autofagia/efeitos dos fármacos; Proteína beta Intensificadora de Ligação a CCAAT/metabolismo; Estimulantes do Sistema Nervoso Central/toxicidade; Metanfetamina/toxicidade; Neurônios/efeitos dos fármacos; Animais; Proteína beta Intensificadora de Ligação a CCAAT/genética; Linhagem Celular Tumoral; Regulação da Expressão Gênica/efeitos dos fármacos; Inativação Gênica; Humanos; Masculino; Neuroblastoma; Ratos; Ratos Sprague-Dawley; Transdução de Sinais/fisiologia; Serina-Treonina Quinases TOR/genética; Serina-Treonina Quinases TOR/metabolismo; Fatores de Transcrição/genética; Fatores de Transcrição/metabolismo; Proteína 2 do Complexo Esclerose Tuberosa/genética; Proteína 2 do Complexo Esclerose Tuberosa/metabolismo; alfa-Sinucleína/genética; alfa-Sinucleína/metabolismo

Palavras-chave

Apoptosis; Autophagy; C/EBPß; Methamphetamine (METH); Neurotoxicity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Apoptose / Proteína beta Intensificadora de Ligação a CCAAT / Estimulantes do Sistema Nervoso Central / Metanfetamina / Neurônios Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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