Protective role of relaxin in a mouse model of aristolochic acid nephropathy.

Yang, Xiu; Thorngren, Daniel; Chen, Qi; Wang, Ming; Xie, Xiangcheng

Yang, Xiu; Thorngren, Daniel; Chen, Qi; Wang, Ming; Xie, Xiangcheng.

Afiliação

Yang X; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Electronic address: yangx_kidney@sina.com.
Thorngren D; Department of Internal Medicine, Jackson Memorial Hospital, 1611 Northwest 12 Avenue, Miami, FL, 33139. USA. Electronic address: daniel.thorngren@jhsmiami.org.
Chen Q; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Electronic address: chenqi1050@njmu.edu.cn.
Wang M; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Internal Medicine, Jackson Memorial Hospital, 1611 Northwest 12 Avenue, Miami, FL, 33139. USA. Electronic address: wangmingdoct@yeah.net.
Xie X; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Internal Medicine, Jackson Memorial Hospital, 1611 Northwest 12 Avenue, Miami, FL, 33139. USA. Electronic address: freemaple@126.com.

Biomed Pharmacother ; 115: 108917, 2019 Jul.

Article em En | MEDLINE | ID: mdl-31060002

Assuntos

Ácidos Aristolóquicos; Rim/efeitos dos fármacos; Nefrite Intersticial/prevenção & controle; Relaxina/uso terapêutico; Animais; Apoptose/efeitos dos fármacos; Linhagem Celular; Modelos Animais de Doenças; Rim/metabolismo; Rim/patologia; Testes de Função Renal; Masculino; Camundongos Endogâmicos C57BL; Nefrite Intersticial/induzido quimicamente; Nefrite Intersticial/metabolismo; Nefrite Intersticial/patologia; Óxido Nítrico Sintase Tipo III/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais

Palavras-chave

Apoptosis; Aristolochic acid nephropathy; Relaxin; Renal fibrosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Relaxina / Ácidos Aristolóquicos / Rim / Nefrite Intersticial Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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