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Recent advances in reaction-based fluorescent probes for detecting monoamine oxidases in living systems.
Huang, Jintao; Hong, Danqi; Lang, Wenjie; Liu, Jian; Dong, Jia; Yuan, Chaonan; Luo, Jie; Ge, Jingyan; Zhu, Qing.
Afiliação
  • Huang J; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. gejy@zjut.edu.cn zhuq@zjut.edu.cn.
  • Hong D; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. gejy@zjut.edu.cn zhuq@zjut.edu.cn.
  • Lang W; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. gejy@zjut.edu.cn zhuq@zjut.edu.cn.
  • Liu J; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. gejy@zjut.edu.cn zhuq@zjut.edu.cn.
  • Dong J; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. gejy@zjut.edu.cn zhuq@zjut.edu.cn.
  • Yuan C; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. gejy@zjut.edu.cn zhuq@zjut.edu.cn.
  • Luo J; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. gejy@zjut.edu.cn zhuq@zjut.edu.cn.
  • Ge J; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. gejy@zjut.edu.cn zhuq@zjut.edu.cn.
  • Zhu Q; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. gejy@zjut.edu.cn zhuq@zjut.edu.cn.
Analyst ; 144(12): 3703-3709, 2019 Jun 21.
Article em En | MEDLINE | ID: mdl-31062779
ABSTRACT
Monoamine oxidase (MAO) is a membrane-bound mitochondrial enzyme that plays an important role by catalyzing oxidative deamination to maintain the homeostasis of neurotransmitters and other biogenic amines in living systems. MAO activity is critical for the brain and central nervous system. Its dysfunction is closely related with many neurological and psychiatric disorders. Fluorescent probes provide a useful approach to accurately detect MAO activity and assist to better elucidate their biological functions. Herein, in this Minireview, we summarize the recent advances in reaction based MAO type fluorescent probes and their imaging applications in living systems.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corantes Fluorescentes / Monoaminoxidase Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corantes Fluorescentes / Monoaminoxidase Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article