Unexpected Friendship: Neutrophils Help Tumor Cells En Route to Metastasis.

Iriondo, Oihana; Yu, Min

Iriondo, Oihana; Yu, Min.

Afiliação

Iriondo O; Department of Stem Cell Biology and Regenerative Medicine and USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Yu M; Department of Stem Cell Biology and Regenerative Medicine and USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: minyu@med.usc.edu.

Dev Cell ; 49(3): 308-310, 2019 05 06.

Article em En | MEDLINE | ID: mdl-31063748

ABSTRACT

ABSTRACT

Circulating tumor cells (CTCs) contain metastatic precursors that can initiate new metastases. Recent work shows that association with neutrophils provides a proliferative advantage to CTCs, rendering them more competent in metastasis formation. The study identifies molecular players in CTC-neutrophil interactions, providing potential targets for disrupting formation of these deadly metastatic seeds.

Assuntos

Células Neoplásicas Circulantes; Ciclo Celular; Amigos; Humanos; Neutrófilos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Neoplásicas Circulantes Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google