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Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells.
Ma, Leyuan; Pak, Magnolia L; Ou, Jianhong; Yu, Jun; St Louis, Pamela; Shan, Yi; Hutchinson, Lloyd; Li, Shaoguang; Brehm, Michael A; Zhu, Lihua Julie; Green, Michael R.
Afiliação
  • Ma L; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
  • Pak ML; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
  • Ou J; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
  • Yu J; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
  • St Louis P; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605.
  • Shan Y; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605.
  • Hutchinson L; Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
  • Li S; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605.
  • Brehm MA; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605.
  • Zhu LJ; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
  • Green MR; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605.
Proc Natl Acad Sci U S A ; 116(21): 10482-10487, 2019 05 21.
Article em En | MEDLINE | ID: mdl-31068472
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Compostos de Bifenilo / Leucemia Mielogênica Crônica BCR-ABL Positiva / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Resistencia a Medicamentos Antineoplásicos / Tiazolidinas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Compostos de Bifenilo / Leucemia Mielogênica Crônica BCR-ABL Positiva / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Resistencia a Medicamentos Antineoplásicos / Tiazolidinas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article