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Results from HARMONY: an open-label, multicenter, 2-arm, phase 1b, dose-finding study assessing the safety and efficacy of the oral combination of ruxolitinib and buparlisib in patients with myelofibrosis.
Durrant, Simon T; Nagler, Arnon; Guglielmelli, Paola; Lavie, David; le Coutre, Philipp; Gisslinger, Heinz; Chuah, Charles; Maffioli, Margherita; Bharathy, Savita; Dong, Tuochuan; Wroclawska, Monika; Lopez, Joaquin Martinez.
Afiliação
  • Durrant ST; Royal Brisbane Hospital, Herston, Australia simon.durrant@iconcancercare.com.au.
  • Nagler A; ALWP Office, Hospital Saint Antoine, Paris, France.
  • Guglielmelli P; CRIMM-Centro Ricerca e Innovazione delle Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Lavie D; Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
  • le Coutre P; Charité, Campus Virchow Klinikum, Universitätsmedizin Berlin, Berlin, Germany.
  • Gisslinger H; Medical University of Vienna, Vienna, Austria.
  • Chuah C; Singapore General Hospital, Duke-NUS Medical School, Singapore.
  • Maffioli M; Hematology Department, ASST Sette Laghi - Ospedale di Circolo, Varese, Italy.
  • Bharathy S; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
  • Dong T; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
  • Wroclawska M; Novartis Pharma AG, Basel, Switzerland.
  • Lopez JM; Hematology Department, Hospital 12 de Octubre, CNIO, Univ Complutense, CIBERONC, Madrid, Spain.
Haematologica ; 104(12): e551-e554, 2019 12.
Article em En | MEDLINE | ID: mdl-31073072
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Mielofibrose Primária Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Mielofibrose Primária Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article