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Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming.
Wang, Huan; Sheehan, Robert P; Palmer, Adam C; Everley, Robert A; Boswell, Sarah A; Ron-Harel, Noga; Ringel, Alison E; Holton, Kristina M; Jacobson, Connor A; Erickson, Alison R; Maliszewski, Laura; Haigis, Marcia C; Sorger, Peter K.
Afiliação
  • Wang H; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: huan_sharon_wang@pku.edu.cn.
  • Sheehan RP; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Palmer AC; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Everley RA; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Boswell SA; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Ron-Harel N; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Ringel AE; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Holton KM; Research Computing, Harvard Medical School, Boston, MA 02115, USA.
  • Jacobson CA; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Erickson AR; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Maliszewski L; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Haigis MC; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Sorger PK; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: peter_sorger@hms.harvard.edu.
Cell Syst ; 8(5): 412-426.e7, 2019 05 22.
Article em En | MEDLINE | ID: mdl-31078528
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Miócitos Cardíacos / Inibidores de Proteínas Quinases / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Miócitos Cardíacos / Inibidores de Proteínas Quinases / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article