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Synthesis and preclinical evaluation of the CRTH2 antagonist [11C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass.
Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim; Sköld, Christian; Larhed, Mats; Weis, Jan; Selvaraju, Ram Kumar; Korsgren, Olle; Eriksson, Olof; Odell, Luke R.
Afiliação
  • Eriksson J; Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden. Electronic address: jonas.eriksson@ilk.uu.se.
  • Roy T; Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
  • Sawadjoon S; Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
  • Bachmann K; Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
  • Sköld C; Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
  • Larhed M; Department of Medicinal Chemistry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Weis J; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
  • Selvaraju RK; Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
  • Korsgren O; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
  • Eriksson O; Department of Medicinal Chemistry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Odell LR; Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden. Electronic address: luke.odell@ilk.uu.se.
Nucl Med Biol ; 71: 1-10, 2019 04.
Article em En | MEDLINE | ID: mdl-31082767
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Prostaglandina / Carbolinas / Radioisótopos de Carbono / Receptores Imunológicos / Tamanho Celular / Células Secretoras de Insulina / Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Prostaglandina / Carbolinas / Radioisótopos de Carbono / Receptores Imunológicos / Tamanho Celular / Células Secretoras de Insulina / Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article