Sleep and female reproduction.
Curr Opin Obstet Gynecol
; 31(4): 222-227, 2019 08.
Article
em En
| MEDLINE
| ID: mdl-31082843
ABSTRACT
PURPOSE OF REVIEW Sleep disturbances are increasing in prevalence in North America. There is growing evidence that poor sleep quality and short sleep duration may adversely affect circadian rhythms, which in turn may affect female reproduction. The objective of this review is to evaluate recent literature on the association between sleep disturbances and female reproduction. RECENT FINDINGS:
There is accumulating evidence that sleep quality and duration are important for female reproduction, but epidemiologic research is limited. Recent studies provide suggestive evidence that sleep disorders are associated with increased menstrual irregularity, subfertility/infertility, and poor pregnancy and birth outcomes. Mechanisms underlying these associations are likely to be multifactorial and complex. In addition to genetics, circadian disruption may impact reproductive outcomes through dysregulation of the hypothalamic-pituitary-adrenal axis, insulin resistance, oxidative stress, and systemic inflammation. Recommendations for future studies include use of prospective study designs; assessment of populations not already experiencing reproductive disorders; more detailed and accurate assessments of sleep such as validated self-reported measures or objective sleep measures (e.g. actigraphy); comprehensive assessment of potential confounders and mediators; and elucidation of biologic mechanisms.SUMMARY:
There is a growing body of literature showing evidence that sleep disturbances influence female reproduction, although further epidemiologic research is needed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reprodução
/
Sono
/
Transtornos do Sono-Vigília
/
Ritmo Circadiano
/
Infertilidade Feminina
/
Ciclo Menstrual
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
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Male
/
Pregnancy
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article