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[Brachytherapy: When needs overtake care offer]. / Curiethérapie : quand les indications dépassent l'offre de soins.
Espenel, Sophie; Limkin, Elaine; Garcia, Max-Adrien; Langrand-Escure, Julien; Vallard, Alexis; Chargari, Cyrus; Magné, Nicolas.
Afiliação
  • Espenel S; Institut de cancérologie Lucien-Neuwirth, département de radiothérapie, 108 bis, avenue Albert-Raimond, BP 60008, 42271 Saint-Priest-en-Jarez cedex, France; Institut Gustave-Roussy, département de radiothérapie, 114, rue Edouard-Vaillant, 94800 Villejuif, France.
  • Limkin E; Institut Gustave-Roussy, département de radiothérapie, 114, rue Edouard-Vaillant, 94800 Villejuif, France.
  • Garcia MA; Institut de cancérologie Lucien-Neuwirth, département de santé publique, 108 bis, avenue Albert-Raimond, BP 60008, 42271 Saint-Priest-en-Jarez cedex, France.
  • Langrand-Escure J; Institut de cancérologie Lucien-Neuwirth, département de radiothérapie, 108 bis, avenue Albert-Raimond, BP 60008, 42271 Saint-Priest-en-Jarez cedex, France.
  • Vallard A; Institut de cancérologie Lucien-Neuwirth, département de radiothérapie, 108 bis, avenue Albert-Raimond, BP 60008, 42271 Saint-Priest-en-Jarez cedex, France.
  • Chargari C; Institut Gustave-Roussy, département de radiothérapie, 114, rue Edouard-Vaillant, 94800 Villejuif, France.
  • Magné N; Institut de cancérologie Lucien-Neuwirth, département de radiothérapie, 108 bis, avenue Albert-Raimond, BP 60008, 42271 Saint-Priest-en-Jarez cedex, France. Electronic address: nicolas.magne@icloire.fr.
Bull Cancer ; 106(6): 584-589, 2019 Jun.
Article em Fr | MEDLINE | ID: mdl-31084914
ABSTRACT
Brachytherapy has the unique characteristic of being able to deliver high doses to a very localized volume, and remains one of the radiotherapy techniques that has an unparalleled therapeutic index. However, its use has been declining in the past years. Globally, only 55 to 88 % of patients with locally advanced cervical cancer benefit from utero-vaginal brachytherapy, despite the fact that it is proven to enhance both progression-free and overall survival. A decline in the use of low dose rate brachytherapy has likewise been described in the treatment of low-risk and favorable intermediate-risk prostate cancers. Several factors could explain this. First, the radiation oncologists who have the proficiency to perform brachytherapy seems to be inadequate, as it is a technique that requires training and expertise for optimal applications. In many cancer care centers, the caseload is insufficient to provide this experience. Second, the increasing use of technically advanced external beam radiation therapy, such as intensity modulated radiation therapy, offers an easier substitute with more lucrative benefits, resulting in decreased utilization of brachytherapy. However, when brachytherapy is not delivered, a poorer survival rate is reported in locally advanced cervical cancer, and is suggested in intermediate and high-risk prostate cancer. The increasing level of evidence of treatment with brachytherapy necessitates an improvement in its accessibility by having more radiation oncologists as well as cancer centers equipped to perform the procedure.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Braquiterapia / Neoplasias Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: Fr Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Braquiterapia / Neoplasias Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: Fr Ano de publicação: 2019 Tipo de documento: Article