Design and Evaluation of Synthetic Terminators for Regulating Mammalian Cell Transgene Expression.

Cheng, Joseph K; Morse, Nicholas J; Wagner, James M; Tucker, Scott K; Alper, Hal S

Cheng, Joseph K; Morse, Nicholas J; Wagner, James M; Tucker, Scott K; Alper, Hal S.

Afiliação

Cheng JK; McKetta Department of Chemical Engineering , The University of Texas at Austin , 200 E Dean Keeton Street, Stop C0400 , Austin , Texas 78712 , United States.
Morse NJ; McKetta Department of Chemical Engineering , The University of Texas at Austin , 200 E Dean Keeton Street, Stop C0400 , Austin , Texas 78712 , United States.
Wagner JM; McKetta Department of Chemical Engineering , The University of Texas at Austin , 200 E Dean Keeton Street, Stop C0400 , Austin , Texas 78712 , United States.
Tucker SK; Institute for Cellular and Molecular Biology , The University of Texas at Austin , 2500 Speedway Avenue , Austin , Texas 78712 , United States.
Alper HS; McKetta Department of Chemical Engineering , The University of Texas at Austin , 200 E Dean Keeton Street, Stop C0400 , Austin , Texas 78712 , United States.

ACS Synth Biol ; 8(6): 1263-1275, 2019 06 21.

Article em En | MEDLINE | ID: mdl-31091408

Assuntos

Engenharia Genética/métodos; Regiões Promotoras Genéticas/genética; Biologia Sintética/métodos; Regiões Terminadoras Genéticas/genética; Transgenes/genética; Células HEK293; Humanos

Palavras-chave

HEK293; HT1080; mRNA half-life; mammalian production host; synthetic terminators

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Engenharia Genética / Regiões Promotoras Genéticas / Regiões Terminadoras Genéticas / Transgenes / Biologia Sintética Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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