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Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina.
Tornabene, Patrizia; Trapani, Ivana; Minopoli, Renato; Centrulo, Miriam; Lupo, Mariangela; de Simone, Sonia; Tiberi, Paola; Dell'Aquila, Fabio; Marrocco, Elena; Iodice, Carolina; Iuliano, Antonella; Gesualdo, Carlo; Rossi, Settimio; Giaquinto, Laura; Albert, Silvia; Hoyng, Carel B; Polishchuk, Elena; Cremers, Frans P M; Surace, Enrico M; Simonelli, Francesca; De Matteis, Maria A; Polishchuk, Roman; Auricchio, Alberto.
Afiliação
  • Tornabene P; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Trapani I; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Minopoli R; Medical Genetics, Department of Translational Medicine, Federico II University, 80131 Naples, Italy.
  • Centrulo M; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Lupo M; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • de Simone S; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Tiberi P; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Dell'Aquila F; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Marrocco E; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Iodice C; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Iuliano A; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Gesualdo C; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Rossi S; Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania L. Vanvitelli, 80131 Naples, Italy.
  • Giaquinto L; Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania L. Vanvitelli, 80131 Naples, Italy.
  • Albert S; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Hoyng CB; Department of Human Genetics and Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 Nijmegen, Netherlands.
  • Polishchuk E; Department of Ophthalmology and Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 Nijmegen, Netherlands.
  • Cremers FPM; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Surace EM; Department of Ophthalmology and Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 Nijmegen, Netherlands.
  • Simonelli F; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • De Matteis MA; Medical Genetics, Department of Translational Medicine, Federico II University, 80131 Naples, Italy.
  • Polishchuk R; Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania L. Vanvitelli, 80131 Naples, Italy.
  • Auricchio A; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
Sci Transl Med ; 11(492)2019 05 15.
Article em En | MEDLINE | ID: mdl-31092694
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retina / Técnicas de Transferência de Genes / Dependovirus / Trans-Splicing / Proteínas de Fluorescência Verde / Inteínas Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retina / Técnicas de Transferência de Genes / Dependovirus / Trans-Splicing / Proteínas de Fluorescência Verde / Inteínas Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article