Overriding the Immune System's Sweet Tooth: Fatty Acids Rile Up Innate Immunity.
Cell
; 177(5): 1088-1090, 2019 05 16.
Article
em En
| MEDLINE
| ID: mdl-31100264
ABSTRACT
Mogilenko et al. dissect mechanisms by which fatty acids lead to a state of heightened innate immunity and inflammation. They reveal a metabolic adaptation to elevated fatty acids that involves a shift in the balance between glycolysis and oxidative phosphorylation and activation of the unfolded protein response, linking the high-fat Western diet to systemic inflammatory disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sinais (Psicologia)
/
Ácidos Graxos
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article