Yvis: antibody high-density alignment visualization and analysis platform with an integrated database.
Nucleic Acids Res
; 47(W1): W490-W495, 2019 07 02.
Article
em En
| MEDLINE
| ID: mdl-31106372
ABSTRACT
As antibodies are a very important tool for diagnosis, therapy, and experimental biology, a large number of antibody structures and sequences have become available in recent years. Therefore, tools that allow the analysis, comparison, and visualization of this large amount of antibody data are crucially needed. We developed the antibody high-density alignment visualization and analysis (Yvis) platform to provide an innovative, robust and high-density data visualization of antibody sequence alignments, called Collier de Diamants. The Yvis platform also provides an integrated structural database, which is updated weekly, and many different search and filter options. This platform can help to formulate hypotheses concerning the key residues in antibody structures or interactions to improve the understanding of antibody properties. The Yvis platform is available at http//bioinfo.icb.ufmg.br/yvis/.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
Alinhamento de Sequência
/
Anticorpos
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article