TGFß-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC.

Gladilin, E; Ohse, S; Boerries, M; Busch, H; Xu, C; Schneider, M; Meister, M; Eils, R

Gladilin, E; Ohse, S; Boerries, M; Busch, H; Xu, C; Schneider, M; Meister, M; Eils, R.

Afiliação

Gladilin E; German Cancer Research Center, Div. Bioinformatics and Omics Data Analytics, Mathematikon - Berliner Str. 41, 69120, Heidelberg, Germany. evgeny.gladilin@gmail.com.
Ohse S; University Heidelberg, BioQuant, Im Neuenheimer Feld 267, 69120, Heidelberg, Germany. evgeny.gladilin@gmail.com.
Boerries M; Leibniz Institute of Plant Genetics and Crop Plant Research, OT Gatersleben Corrensstrasse 3, 06466, Seeland, Germany. evgeny.gladilin@gmail.com.
Busch H; University of Freiburg, Institute of Molecular Medicine and Cell Research (IMMZ), Stefan-Meier-Str. 17, 79104, Freiburg, Germany.
Xu C; University of Freiburg, Institute of Molecular Medicine and Cell Research (IMMZ), Stefan-Meier-Str. 17, 79104, Freiburg, Germany.
Schneider M; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Meister M; Department for Biometry, Epidemiology and Medical Bioinformatics and Comprehensive Cancer Center Freiburg (CCCF), University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Breisacherstrasse 153, 79110, Freiburg, Germany.
Eils R; University of Freiburg, Institute of Molecular Medicine and Cell Research (IMMZ), Stefan-Meier-Str. 17, 79104, Freiburg, Germany.

Sci Rep ; 9(1): 7667, 2019 05 21.

Article em En | MEDLINE | ID: mdl-31113982

Assuntos

Carcinoma Pulmonar de Células não Pequenas/metabolismo; Citoesqueleto/metabolismo; Neoplasias Pulmonares/metabolismo; Fator de Crescimento Transformador beta/farmacologia; Idoso; Carcinoma Pulmonar de Células não Pequenas/patologia; Linhagem Celular Tumoral; Movimento Celular; Citoesqueleto/efeitos dos fármacos; Citoesqueleto/patologia; Feminino; Humanos; Neoplasias Pulmonares/patologia; Masculino; Fenômenos Mecânicos; Pessoa de Meia-Idade; Cadeias Pesadas de Miosina/genética; Cadeias Pesadas de Miosina/metabolismo; Invasividade Neoplásica; Vimentina/genética; Vimentina/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citoesqueleto / Fator de Crescimento Transformador beta / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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