Serum Amyloid A is a Novel Inflammatory Biomarker in Polycystic Ovary Syndrome.
Clin Lab
; 65(5)2019 May 01.
Article
em En
| MEDLINE
| ID: mdl-31115233
ABSTRACT
BACKGROUND:
Serum amyloid A (SAA) is considered a biomarker of inflammation; however, the SAA levels in polycystic ovary syndrome (PCOS) are still uncertain.METHODS:
In this study, SAA, glucose, insulin, C-reactive protein (CRP), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and total testosterone concentrations were measured in 82 women with PCOS and 60 healthy controls.RESULTS:
The median concentration of SAA was 5.000 mg/L (IQR 2.825 - 5.400) in women with PCOS, which was significantly higher than that of controls (3.700 mg/L, IQR 2.825 - 5.400, p = 0.025). SAA was only positively associated with the CRP (r = 0.303, p = 0.006). No significant association was observed between SAA and body mass index (BMI), total testosterone, or insulin resistance (IR).CONCLUSIONS:
SAA levels were increased in women with PCOS, and SAA may be a potential inflammatory biomarker for PCOS.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Ovário Policístico
/
Proteína Amiloide A Sérica
/
Biomarcadores
/
Inflamação
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article