Refractory healing after surgical therapy of osteonecrosis of the jaw: associated risk factors in aged patients.
Clin Interv Aging
; 14: 797-804, 2019.
Article
em En
| MEDLINE
| ID: mdl-31123397
ABSTRACT
Purpose:
Osteonecrosis of the jaw (ONJ), both medication-related and non medication-related, mainly occurs in aged patients. It needs surgical intervention. Refractory healing after an operation of ONJ can significantly lower the quality of life of elderly patients. The purpose of this study was to determine risk factors associated with refractory healing in aged patients. Patients andmethods:
We performed a retrospective study of ONJ in aged patients who underwent surgical treatments in a single institute during a 12-year period. Multiple logistic regression analysis was used to determine independent risk factors associated with refractory healing.Results:
A total of 122 patients were included. Of them, 25 patients were identified as the refractory group and 97 patients as the control group. Diabetes mellitus (DM) (AOR=5.03, 95% CI 1.74-14.52) and glucocorticoid administration (AOR=7.97, 95% CI 2.52-25.23) were found to be significant risk factors for refractory healing of ONJ.Conclusion:
DM and medication of glucocorticoid might be risk factors for refractory healing of ONJ.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteonecrose
/
Cicatrização
/
Doenças Maxilomandibulares
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article