A Bird's-Eye View of the Multiple Biochemical Mechanisms that Propel Pathology of Alzheimer's Disease: Recent Advances and Mechanistic Perspectives on How to Halt the Disease Progression Targeting Multiple Pathways.

Vegh, Caleb; Stokes, Kyle; Ma, Dennis; Wear, Darcy; Cohen, Jerome; Ray, Sidhartha D; Pandey, Siyaram

Vegh, Caleb; Stokes, Kyle; Ma, Dennis; Wear, Darcy; Cohen, Jerome; Ray, Sidhartha D; Pandey, Siyaram.

Afiliação

Vegh C; Department of Chemistry and Biochemistry University of Windsor, Ontario, Canada.
Stokes K; Department of Chemistry and Biochemistry University of Windsor, Ontario, Canada.
Ma D; Department of Chemistry and Biochemistry University of Windsor, Ontario, Canada.
Wear D; Department of Chemistry and Biochemistry University of Windsor, Ontario, Canada.
Cohen J; Department of Psychology University of Windsor, Ontario, Canada.
Ray SD; Department of Pharmaceutical and Biomedical Sciences, Touro College of Pharmacy and School of Medicine, Manhattan, NY, USA.
Pandey S; Department of Chemistry and Biochemistry University of Windsor, Ontario, Canada.

J Alzheimers Dis ; 69(3): 631-649, 2019.

Article em En | MEDLINE | ID: mdl-31127770

Assuntos

Doença de Alzheimer/patologia; Transdução de Sinais/efeitos dos fármacos; Doença de Alzheimer/tratamento farmacológico; Animais; Autofagia; Progressão da Doença; Humanos; Estresse Oxidativo

Palavras-chave

Alzheimer's disease; amyloid-ß plaques; ashwagandha; autophagy; mitochondrial dysfunction; oxidative stress; presenilin-1; water-soluble coenzyme-Q10

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Doença de Alzheimer Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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