Cellular context-dependent interaction between cancer and stellate cells in hetero-type multicellular spheroids of pancreatic tumor.

Nam, Sanghun; Khawar, Iftikhar Ali; Park, Jong Kook; Chang, Suhwan; Kuh, Hyo-Jeong

Nam, Sanghun; Khawar, Iftikhar Ali; Park, Jong Kook; Chang, Suhwan; Kuh, Hyo-Jeong.

Afiliação

Nam S; Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: sanghun88mir@nate.com.
Khawar IA; Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: sakhawatali59@gmail.com.
Park JK; Department of Biomedical Science, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Republic of Korea. Electronic address: jkp555@hallym.ac.kr.
Chang S; Department of Biomedical Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea. Electronic address: suhwan.chang@amc.seoul.kr.
Kuh HJ; Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul, Republic of Korea; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: hkuh@catholic.ac.kr.

Biochem Biophys Res Commun ; 515(1): 183-189, 2019 07 12.

Article em En | MEDLINE | ID: mdl-31133378

Assuntos

Carcinoma Ductal Pancreático/metabolismo; Comunicação Celular; Neoplasias Pancreáticas/metabolismo; Células Estreladas do Pâncreas/metabolismo; Antimetabólitos Antineoplásicos/farmacologia; Caderinas/metabolismo; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; Técnicas de Cocultura; Desoxicitidina/análogos & derivados; Desoxicitidina/farmacologia; Transição Epitelial-Mesenquimal/efeitos dos fármacos; Humanos; Neoplasias Pancreáticas/patologia; Células Estreladas do Pâncreas/citologia; Esferoides Celulares/efeitos dos fármacos; Microambiente Tumoral/efeitos dos fármacos; Vimentina/metabolismo; Gencitabina

Palavras-chave

Co-culture; Epithelial-mesenchymal transition; Gemcitabine sensitivity; Pancreatic cancer; Pancreatic stellate cells; Spheroid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Comunicação Celular / Carcinoma Ductal Pancreático / Células Estreladas do Pâncreas Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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