Prospect and challenge of detecting dynamic gene copy number increases in stem cells by whole genome sequencing.

Fischer, Ulrike; Backes, Christina; Fehlmann, Tobias; Galata, Valentina; Keller, Andreas; Meese, Eckart

Fischer, Ulrike; Backes, Christina; Fehlmann, Tobias; Galata, Valentina; Keller, Andreas; Meese, Eckart.

Afiliação

Fischer U; Department of Human Genetics, Saarland University, Building 60, 66421, Homburg/Saar, Germany. ulrike.fischer@uks.eu.
Backes C; Clinical Bioinformatics, Saarland University, Building E2.1, 66123, Saarbrücken, Germany.
Fehlmann T; Clinical Bioinformatics, Saarland University, Building E2.1, 66123, Saarbrücken, Germany.
Galata V; Clinical Bioinformatics, Saarland University, Building E2.1, 66123, Saarbrücken, Germany.
Keller A; Clinical Bioinformatics, Saarland University, Building E2.1, 66123, Saarbrücken, Germany.
Meese E; Department of Human Genetics, Saarland University, Building 60, 66421, Homburg/Saar, Germany.

J Mol Med (Berl) ; 97(8): 1099-1111, 2019 08.

Article em En | MEDLINE | ID: mdl-31134286

Assuntos

Amplificação de Genes; Dosagem de Genes; Células-Tronco Mesenquimais; Células-Tronco Neurais; Sequenciamento Completo do Genoma; Linhagem Celular; Humanos

Palavras-chave

CDK4; Gene amplification; Neural stem cell; SHANK3; WGS

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Amplificação de Genes / Dosagem de Genes / Células-Tronco Neurais / Células-Tronco Mesenquimais / Sequenciamento Completo do Genoma Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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