Your browser doesn't support javascript.
loading
Isolated pancreatic metastasis from malignant melanoma: a case report and literature review.
Nakamura, Yoshifumi; Yamada, Reiko; Kaneko, Maki; Naota, Hiroaki; Fujimura, Yu; Tabata, Masami; Kobayashi, Kazuhiko; Tanaka, Kyosuke.
Afiliação
  • Nakamura Y; Department of Gastroenterology, Matsusaka Chuo General Hospital, Matsusaka, Mie, Japan.
  • Yamada R; Department of Gastroenterology and Hepatology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. reiko-t@clin.medic.mie-u.ac.jp.
  • Kaneko M; Department of Gastroenterology, Matsusaka Chuo General Hospital, Matsusaka, Mie, Japan.
  • Naota H; Department of Gastroenterology, Matsusaka Chuo General Hospital, Matsusaka, Mie, Japan.
  • Fujimura Y; Department of Surgery, Matsusaka Chuo General Hospital, Matsusaka, Mie, Japan.
  • Tabata M; Department of Surgery, Matsusaka Chuo General Hospital, Matsusaka, Mie, Japan.
  • Kobayashi K; Department of Gastroenterology, Matsusaka Chuo General Hospital, Matsusaka, Mie, Japan.
  • Tanaka K; Department of Endoscopy, Mie University Hospital, Tsu, Mie, Japan.
Clin J Gastroenterol ; 12(6): 626-636, 2019 Dec.
Article em En | MEDLINE | ID: mdl-31134450
ABSTRACT
Isolated pancreatic metastasis from malignant melanoma is rare. Pancreatic metastasis is difficult to diagnose in patients with unknown primary malignant melanoma. Endoscopic ultrasound-guided fine-needle aspiration plays an important role in confirming the diagnosis. A 67-year-old woman was referred to our institution because of a mass in her pancreas. Computed tomography and magnetic resonance imaging revealed a 35-mm mass localized on the pancreatic tail, with low attenuation, surrounded by a high-attenuation rim. Endoscopic ultrasonography revealed a hypoechoic mass with central anechoic areas. Endoscopic ultrasound-guided fine-needle aspiration of the mass was performed, and the pathological diagnosis was malignant melanoma. Intense fluorodeoxyglucose uptake was observed in the pancreatic tail on positron emission tomography-computed tomography. No other malignant melanoma was found. Distal pancreatectomy was performed. Six months postoperatively, positron emission tomography-computed tomography revealed high uptake in the left nasal cavity, and biopsy revealed the mass to be a malignant melanoma, indicating that the primary site of the malignant melanoma was the left nasal cavity and that the pancreatic mass and peritoneal lesion were metastases. The patient had survived > 2 years after the distal pancreatectomy. Pancreatic resection of isolated pancreatic metastasis can possibly prolong survival; however, metastatic melanoma usually has poor prognosis.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Neoplasias Cutâneas / Neoplasias Nasais / Melanoma Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Neoplasias Cutâneas / Neoplasias Nasais / Melanoma Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article