Reduced vancomycin susceptibility and increased macrophage survival in Staphylococcus aureus strains sequentially isolated from a bacteraemic patient during a short course of antibiotic therapy.

Basco, M D S; Kothari, A; McKinzie, Page B; Revollo, J R; Agnihothram, S; Azevedo, M P; Saccente, M; Hart, M E

Basco, M D S; Kothari, A; McKinzie, Page B; Revollo, J R; Agnihothram, S; Azevedo, M P; Saccente, M; Hart, M E.

Afiliação

Basco MDS; 1 Division of Microbiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, USA.
Kothari A; 2 Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
McKinzie PB; 3 Division of Molecular and Genetic Toxicology, NCTR, Food and Drug Administration, Jefferson, Arkansas, USA.
Revollo JR; 3 Division of Molecular and Genetic Toxicology, NCTR, Food and Drug Administration, Jefferson, Arkansas, USA.
Agnihothram S; 1 Division of Microbiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, USA.
Azevedo MP; 1 Division of Microbiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, USA.
Saccente M; 2 Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Hart ME; 1 Division of Microbiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, USA.

J Med Microbiol ; 68(6): 848-859, 2019 Jun.

Article em En | MEDLINE | ID: mdl-31136294

Assuntos

Antibacterianos/farmacologia; Macrófagos/fisiologia; Infecções Estafilocócicas/microbiologia; Staphylococcus aureus/genética; Resistência a Vancomicina/genética; Vancomicina/farmacologia; Idoso; Bacteriemia/microbiologia; Parede Celular/efeitos dos fármacos; Daptomicina/farmacologia; Humanos; Lisostafina/farmacologia; Masculino; Testes de Sensibilidade Microbiana; Tipagem de Sequências Multilocus; Mutação; Infecções Estafilocócicas/tratamento farmacológico; Staphylococcus aureus/efeitos dos fármacos; Staphylococcus aureus/virologia

Palavras-chave

Staphylococcus aureus; hVISA; resilence to immunoclearance; vancomycin resistance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Estafilocócicas / Staphylococcus aureus / Vancomicina / Resistência a Vancomicina / Macrófagos / Antibacterianos Limite: Aged / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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