Extracellular cold inducible RNA-binding protein mediates binge alcohol-induced brain hypoactivity and impaired cognition in mice.

Jacob, Asha; Ma, Yilong; Nasiri, Elham; Ochani, Mahendar; Carrion, Joseph; Peng, Shichun; Brenner, Max; Huerta, Patricio T; Wang, Ping

Jacob, Asha; Ma, Yilong; Nasiri, Elham; Ochani, Mahendar; Carrion, Joseph; Peng, Shichun; Brenner, Max; Huerta, Patricio T; Wang, Ping.

Afiliação

Jacob A; Immunology and Inflammation, Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA. avarghes@northwell.edu.
Ma Y; Department of Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA. avarghes@northwell.edu.
Nasiri E; Center for Neurosciences, Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Ochani M; Laboratory of Immune & Neural Networks, Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Carrion J; Immunology and Inflammation, Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Peng S; Center for Neurosciences, Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Brenner M; Center for Neurosciences, Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Huerta PT; Immunology and Inflammation, Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Wang P; Department of Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

Mol Med ; 25(1): 24, 2019 05 30.

Article em En | MEDLINE | ID: mdl-31146675

Assuntos

Consumo Excessivo de Bebidas Alcoólicas/complicações; Encéfalo/efeitos dos fármacos; Encéfalo/metabolismo; Disfunção Cognitiva/tratamento farmacológico; Proteínas de Ligação a RNA/metabolismo; Tonsila do Cerebelo/efeitos dos fármacos; Tonsila do Cerebelo/metabolismo; Animais; Disfunção Cognitiva/genética; Disfunção Cognitiva/metabolismo; Fluordesoxiglucose F18/análise; Hipocampo/efeitos dos fármacos; Hipocampo/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Mutantes; Tomografia por Emissão de Pósitrons; Proteínas de Ligação a RNA/genética; Memória Espacial/efeitos dos fármacos

Palavras-chave

Amygdala; CIRP; Fluorodeoxyglucose; Hippocampus; Spatial memory; microPET

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Proteínas de Ligação a RNA / Disfunção Cognitiva / Consumo Excessivo de Bebidas Alcoólicas Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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