Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models.

Kukuyan, Anna-Mariya; Sementino, Eleonora; Kadariya, Yuwaraj; Menges, Craig W; Cheung, Mitchell; Tan, Yinfei; Cai, Kathy Q; Slifker, Michael J; Peri, Suraj; Klein-Szanto, Andres J; Rauscher, Frank J; Testa, Joseph R

Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models.

Kukuyan, Anna-Mariya; Sementino, Eleonora; Kadariya, Yuwaraj; Menges, Craig W; Cheung, Mitchell; Tan, Yinfei; Cai, Kathy Q; Slifker, Michael J; Peri, Suraj; Klein-Szanto, Andres J; Rauscher, Frank J; Testa, Joseph R.

Afiliação

Kukuyan AM; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Sementino E; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Kadariya Y; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Menges CW; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Cheung M; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Tan Y; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Cai KQ; Histopathology Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Slifker MJ; Bioinformatics and Biostatistics Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Peri S; Bioinformatics and Biostatistics Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Klein-Szanto AJ; Histopathology Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Rauscher FJ; Wistar Institute, Philadelphia, Pennsylvania.
Testa JR; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania. joseph.testa@fccc.edu.

Cancer Res ; 79(16): 4113-4123, 2019 08 15.

Article em En | MEDLINE | ID: mdl-31151962

Assuntos

Inibidor p16 de Quinase Dependente de Ciclina/genética; Neoplasias Pulmonares/patologia; Mesotelioma/patologia; Neurofibromina 2/genética; Neoplasias Pleurais/patologia; Proteínas Supressoras de Tumor/genética; Ubiquitina Tiolesterase/genética; Animais; Inibidor p16 de Quinase Dependente de Ciclina/metabolismo; Regulação Neoplásica da Expressão Gênica; Neoplasias Pulmonares/genética; Mesotelioma/genética; Mesotelioma Maligno; Camundongos Knockout; Neurofibromina 2/metabolismo; Neoplasias Pleurais/genética; Complexo Repressor Polycomb 2/genética; Complexo Repressor Polycomb 2/metabolismo; Proteínas Supressoras de Tumor/metabolismo; Ubiquitina Tiolesterase/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pleurais / Inibidor p16 de Quinase Dependente de Ciclina / Neurofibromina 2 / Proteínas Supressoras de Tumor / Ubiquitina Tiolesterase / Neoplasias Pulmonares / Mesotelioma Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google