AVRA: Automatic visual ratings of atrophy from MRI images using recurrent convolutional neural networks.
Neuroimage Clin
; 23: 101872, 2019.
Article
em En
| MEDLINE
| ID: mdl-31154242
ABSTRACT
Quantifying the degree of atrophy is done clinically by neuroradiologists following established visual rating scales. For these assessments to be reliable the rater requires substantial training and experience, and even then the rating agreement between two radiologists is not perfect. We have developed a model we call AVRA (Automatic Visual Ratings of Atrophy) based on machine learning methods and trained on 2350 visual ratings made by an experienced neuroradiologist. It provides fast and automatic ratings for Scheltens' scale of medial temporal atrophy (MTA), the frontal subscale of Pasquier's Global Cortical Atrophy (GCA-F) scale, and Koedam's scale of Posterior Atrophy (PA). We demonstrate substantial inter-rater agreement between AVRA's and a neuroradiologist ratings with Cohen's weighted kappa values of κwâ¯=â¯0.74/0.72 (MTA left/right), κwâ¯=â¯0.62 (GCA-F) and κwâ¯=â¯0.74 (PA). We conclude that automatic visual ratings of atrophy can potentially have great scientific value, and aim to present AVRA as a freely available toolbox.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Atrofia
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Encéfalo
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Interpretação de Imagem Assistida por Computador
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Redes Neurais de Computação
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Neuroimagem
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article