Variable Baseline <i>Papio cynocephalus</i> Endogenous Retrovirus (PcEV) Expression Is Upregulated in Acutely SIV-Infected Macaques and Correlated to STAT1 Expression in the Spleen.

Maze, Emmanuel Atangana; Ham, Claire; Kelly, Jack; Ussher, Lindsay; Almond, Neil; Towers, Greg J; Berry, Neil; Belshaw, Robert

Variable Baseline Papio cynocephalus Endogenous Retrovirus (PcEV) Expression Is Upregulated in Acutely SIV-Infected Macaques and Correlated to STAT1 Expression in the Spleen.

Maze, Emmanuel Atangana; Ham, Claire; Kelly, Jack; Ussher, Lindsay; Almond, Neil; Towers, Greg J; Berry, Neil; Belshaw, Robert.

Afiliação

Maze EA; School of Biomedical Sciences, Faculty of Medicine and Dentistry, University of Plymouth, Plymouth, United Kingdom.
Ham C; Division of Infectious Disease Diagnostics, National Institute of Standards and Control (NIBSC), Potters Bar, United Kingdom.
Kelly J; Division of Infectious Disease Diagnostics, National Institute of Standards and Control (NIBSC), Potters Bar, United Kingdom.
Ussher L; School of Biomedical Sciences, Faculty of Medicine and Dentistry, University of Plymouth, Plymouth, United Kingdom.
Almond N; School of Biomedical Sciences, Faculty of Medicine and Dentistry, University of Plymouth, Plymouth, United Kingdom.
Towers GJ; Division of Infectious Disease Diagnostics, National Institute of Standards and Control (NIBSC), Potters Bar, United Kingdom.
Berry N; Division of Infection and Immunity, University College London, London, United Kingdom.
Belshaw R; Division of Infectious Disease Diagnostics, National Institute of Standards and Control (NIBSC), Potters Bar, United Kingdom.

Front Immunol ; 10: 901, 2019.

Article em En | MEDLINE | ID: mdl-31156613

Assuntos

Retrovirus Endógenos/genética; Retrovirus Endógenos/metabolismo; Fator de Transcrição STAT1/metabolismo; Síndrome de Imunodeficiência Adquirida dos Símios/sangue; Vírus da Imunodeficiência Símia/genética; Baço/metabolismo; Regulação para Cima/genética; Doença Aguda; Animais; Sequência de Bases; DNA Viral/genética; Loci Gênicos; Macaca fascicularis; Macaca mulatta; Fases de Leitura Aberta/genética; RNA Viral/sangue; RNA Viral/genética; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Síndrome de Imunodeficiência Adquirida dos Símios/patologia; Síndrome de Imunodeficiência Adquirida dos Símios/virologia; Replicação Viral/genética

Palavras-chave

PcEV; RNA; SIV; STAT1; endogenous retrovirus; innate immunity; macaque

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Baço / Regulação para Cima / Síndrome de Imunodeficiência Adquirida dos Símios / Vírus da Imunodeficiência Símia / Retrovirus Endógenos / Fator de Transcrição STAT1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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