High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension.

Ferguson, Jane F; Aden, Luul A; Barbaro, Natalia R; Van Beusecum, Justin P; Xiao, Liang; Simmons, Alan J; Warden, Cassandra; Pasic, Lejla; Himmel, Lauren E; Washington, Mary K; Revetta, Frank L; Zhao, Shilin; Kumaresan, Shivani; Scholz, Matthew B; Tang, Zhengzheng; Chen, Guanhua; Reilly, Muredach P; Kirabo, Annet

Ferguson, Jane F; Aden, Luul A; Barbaro, Natalia R; Van Beusecum, Justin P; Xiao, Liang; Simmons, Alan J; Warden, Cassandra; Pasic, Lejla; Himmel, Lauren E; Washington, Mary K; Revetta, Frank L; Zhao, Shilin; Kumaresan, Shivani; Scholz, Matthew B; Tang, Zhengzheng; Chen, Guanhua; Reilly, Muredach P; Kirabo, Annet.

Afiliação

Ferguson JF; Division of Cardiovascular Medicine, Department of Medicine.
Aden LA; Vanderbilt Translational and Clinical Cardiovascular Research Center.
Barbaro NR; Division of Clinical Pharmacology, Department of Medicine, and.
Van Beusecum JP; Division of Clinical Pharmacology, Department of Medicine, and.
Xiao L; Division of Clinical Pharmacology, Department of Medicine, and.
Simmons AJ; Division of Clinical Pharmacology, Department of Medicine, and.
Warden C; Division of Clinical Pharmacology, Department of Medicine, and.
Pasic L; Division of Clinical Pharmacology, Department of Medicine, and.
Himmel LE; Division of Clinical Pharmacology, Department of Medicine, and.
Washington MK; Division of Comparative Medicine, Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Revetta FL; Division of Comparative Medicine, Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Zhao S; Division of Comparative Medicine, Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Kumaresan S; Department of Biostatistics and.
Scholz MB; Division of Clinical Pharmacology, Department of Medicine, and.
Tang Z; Vanderbilt Technologies for Advanced Genomics core facility, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Chen G; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin.
Reilly MP; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin.
Kirabo A; Cardiology Division, Department of Medicine, Columbia University Medical Center, New York, New York, USA.

JCI Insight ; 52019 06 04.

Article em En | MEDLINE | ID: mdl-31162138

Assuntos

Células Dendríticas/efeitos dos fármacos; Células Dendríticas/metabolismo; Disbiose; Hipertensão/metabolismo; Cloreto de Sódio na Dieta/efeitos adversos; Cloreto de Sódio/efeitos adversos; Adolescente; Transferência Adotiva; Adulto; Angiotensina II; Animais; Aorta/metabolismo; Bactérias/classificação; Bactérias/genética; Pressão Sanguínea; Antígeno CD11c/imunologia; Colo/microbiologia; Colo/patologia; Citocinas/metabolismo; Células Dendríticas/patologia; Modelos Animais de Doenças; Feminino; Microbioma Gastrointestinal; Humanos; Inflamação/metabolismo; Lipídeos; Linfonodos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Pessoa de Meia-Idade; Células Mieloides/metabolismo; Nódulos Linfáticos Agregados/microbiologia; Nódulos Linfáticos Agregados/patologia; RNA Ribossômico 16S/genética; Cloreto de Sódio/administração & dosagem; Cloreto de Sódio na Dieta/administração & dosagem; Adulto Jovem

Palavras-chave

Hypertension; Inflammation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Cloreto de Sódio / Cloreto de Sódio na Dieta / Disbiose / Hipertensão Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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