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An Antitumor Bis(N-Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target.
Hu, Di; Yang, Chen; Lok, Chun-Nam; Xing, Fangrong; Lee, Pui-Yan; Fung, Yi Man Eva; Jiang, Haibo; Che, Chi-Ming.
Afiliação
  • Hu D; State Key Laboratory of Synthetic Chemistry, Aglaia-KEIIT Laboratory for Drug Discovery and Development and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
  • Yang C; State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
  • Lok CN; HKU Shenzhen Institute of Research and Innovation, Shenzhen, China.
  • Xing F; State Key Laboratory of Synthetic Chemistry, Aglaia-KEIIT Laboratory for Drug Discovery and Development and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
  • Lee PY; State Key Laboratory of Synthetic Chemistry, Aglaia-KEIIT Laboratory for Drug Discovery and Development and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
  • Fung YME; State Key Laboratory of Synthetic Chemistry, Aglaia-KEIIT Laboratory for Drug Discovery and Development and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
  • Jiang H; State Key Laboratory of Synthetic Chemistry, Aglaia-KEIIT Laboratory for Drug Discovery and Development and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
  • Che CM; School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia.
Angew Chem Int Ed Engl ; 58(32): 10914-10918, 2019 08 05.
Article em En | MEDLINE | ID: mdl-31165553
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organoplatínicos / Aspartato-Amônia Ligase / Inibidores Enzimáticos / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organoplatínicos / Aspartato-Amônia Ligase / Inibidores Enzimáticos / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article