Open reading frame mining identifies a TLR4 binding domain in the primary sequence of ECRG4.

Dang, Xitong; Coimbra, Raul; Mao, Liang; Podvin, Sonia; Li, Xue; Yu, Hua; Costantini, Todd W; Zeng, Xiaorong; Larocca, Dana; Eliceiri, Brian P; Baird, Andrew

Dang, Xitong; Coimbra, Raul; Mao, Liang; Podvin, Sonia; Li, Xue; Yu, Hua; Costantini, Todd W; Zeng, Xiaorong; Larocca, Dana; Eliceiri, Brian P; Baird, Andrew.

Afiliação

Dang X; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA.
Coimbra R; The Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, China.
Mao L; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA.
Podvin S; The Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, China.
Li X; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA.
Yu H; The Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, China.
Costantini TW; The Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, China.
Zeng X; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA.
Larocca D; The Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, China.
Eliceiri BP; Mandala Biosciences, San Diego, CA, USA.
Baird A; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA.

Cell Mol Life Sci ; 76(24): 5027-5039, 2019 Dec.

Article em En | MEDLINE | ID: mdl-31190084

Assuntos

Imunidade Inata/genética; Neoplasias da Próstata/genética; Receptor 4 Toll-Like/genética; Proteínas Supressoras de Tumor/genética; Linhagem Celular Tumoral; Movimento Celular/genética; Técnicas de Visualização da Superfície Celular; Genes Supressores de Tumor; Humanos; Interações Hidrofóbicas e Hidrofílicas; Ligantes; Masculino; NF-kappa B/genética; Oligonucleotídeos/genética; Fases de Leitura Aberta/genética; Neoplasias da Próstata/patologia; Domínios Proteicos/genética; Transfecção

Palavras-chave

Cytokine precursor; Ligand; Peptide targeting; Phage display; Receptor; Secretome; Tumor suppressor gene

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Proteínas Supressoras de Tumor / Receptor 4 Toll-Like / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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