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Targeting IRAK4 disrupts inflammatory pathways and delays tumor development in chronic lymphocytic leukemia.
Giménez, Neus; Schulz, Ralph; Higashi, Morihiro; Aymerich, Marta; Villamor, Neus; Delgado, Julio; Juan, Manel; López-Guerra, Mònica; Campo, Elias; Rosich, Laia; Seiffert, Martina; Colomer, Dolors.
Afiliação
  • Giménez N; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), CIBERONC, Barcelona, Spain.
  • Schulz R; Anaxomics Biotech, Barcelona, Spain.
  • Higashi M; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Aymerich M; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Villamor N; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), CIBERONC, Barcelona, Spain.
  • Delgado J; Hematopathology Unit, Department of Pathology, Hospital Clinic, IDIBAPS, CIBERONC, Barcelona, Spain.
  • Juan M; Hematopathology Unit, Department of Pathology, Hospital Clinic, IDIBAPS, CIBERONC, Barcelona, Spain.
  • López-Guerra M; Department of Hematology, Hospital Clinic, IDIBAPS, CIBERONC, Barcelona, Spain.
  • Campo E; Department of Immunology, Hospital Clinic, HSJD-HCB Immunotherapy Platform, IDIBAPS, Barcelona, Spain.
  • Rosich L; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), CIBERONC, Barcelona, Spain.
  • Seiffert M; Hematopathology Unit, Department of Pathology, Hospital Clinic, IDIBAPS, CIBERONC, Barcelona, Spain.
  • Colomer D; Hematopathology Unit, Department of Pathology, Hospital Clinic, IDIBAPS, CIBERONC, Barcelona, Spain.
Leukemia ; 34(1): 100-114, 2020 01.
Article em En | MEDLINE | ID: mdl-31197259
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Transdução de Sinais / Quinases Associadas a Receptores de Interleucina-1 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Transdução de Sinais / Quinases Associadas a Receptores de Interleucina-1 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article